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Hepatic Encephalopathy Information Center

Hepatic Encephalopathy, sometimes referred to as portosystemic encephalopathy or PSE, is a condition that causes temporary worsening of brain function in people with advanced liver disease. When your liver is damaged it can no longer remove toxic substances from your blood. These toxins build up and can travel through your body until they reach your brain, causing mental and physical symptoms of HE.

Explore this Hepatic Encephalopathy Information Center by clicking through to the Diagnosis, Treatment, Support and Caregivers landing pages where you’ll find more information to help you manage Hepatic Encephalopathy.


Learn if you or someone you love is at risk of getting HE, what triggers this complication and how it’s exhibited.


Being confronted with a diagnosis of HE can be overwhelming. And because HE is a complicated condition, a multidisciplinary approach is often required to manage it.


If you’re living with HE or caring for a loved one with HE you’ll likely need emotional, physical or financial support at certain points in your journey.

Caregiver and patient

Simply put, a caregiver is anyone who is responsible for the daily needs of another person. Caregivers can be a friend, spouse, life partner, parent, sibling or other family member.

  1. Hepatic Encephalopathy is a brain disorder that develops in some individuals with liver disease.
  2. Approximately 70% of individuals with cirrhosis may develop symptoms of Hepatic Encephalopathy.
  3. In some cases, Hepatic Encephalopathy is a short-term problem that can be corrected. It may also occur as part of a chronic problem from liver disease that gets worse over time.

Angie M.

Caregiver for Brother…
Faces of Liver Disease

Charles D.

Hepatic Encephalopathy


Hepatic Encephalopathy Hepatitis C End Stage Liver Disease
Faces of Liver Disease

Jason D.

Alcohol-related Cirrhosis
Silhouette Man

Jeremiah B.

Caregiver for Wife…
Silhouette Woman

Joyce O.

Caregiver for Mother…

Karen S.

Primary Biliary Cholangitis
Lynette K

Lynette K.

Hepatic Encephalopathy

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