Liver Disease Lookup

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Acute Hepatic Porphyria (AHP)

Acute Hepatic Porphyria is a family of rare genetic diseases characterized by potentially life-threatening attacks and chronic pain that interfere in their ability to live normal lives.

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Alcohol-Associated Liver Disease

Alcohol-related liver disease is caused by excessive consumption of alcohol and is a common, but preventable, disease. For most people, moderate drinking will not lead to the disease.

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Alpha-1 Antitrypsin Deficiency

Alpha-1 antitrypsin deficiency (Alpha-1) is the most common genetic cause of liver disease in children. Adults can also be affected by Alpha-1 and may develop lung conditions such as emphysema, as well as other liver problems.

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Ascites

The increased pressure of portal hypertension causes fluid to seep out and pool in the abdominal cavity. This is called ascites.

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Autoimmune Liver Diseases

An autoimmune liver disease develops when your own immune system mistakes normal, healthy tissue for a foreign body. As a result, the immune system attacks healthy liver cells (as with AIH) or bile duct cells (PSC, PBC). 

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Benign Liver Tumors

A tumor is an abnormal growth of cells or tissues. Some tumors are malignant, or cancerous. Others are benign, or noncancerous.

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Bile Duct Cancer (Cholangiocarcinoma)

Bile duct cancer (cholangiocarcinoma) is the formation of malignant (cancerous) tumors in these tubes or ducts.

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Cancer

Cancer is the growth and spread of unhealthy cells in the body.

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Cirrhosis of the Liver

As cirrhosis becomes worse, the liver will have less healthy tissue. If cirrhosis is not treated, the liver will fail and will not be able to work well or at all.

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Complications of Liver Disease

Many forms of liver disease come with varying forms of complications associated with its progression.

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Diagnosing Liver Disease

Diagnosing liver disease may involve liver function tests, a liver biopsy and more advanced forms of imaging.

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Fatty Liver Disease (Steatotic Liver Disease)

Fatty liver disease is a condition in which excess fat is stored inside liver cells, making it harder for the liver to function.

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Gilbert Syndrome

Gilbert Syndrome is a mild genetic disorder in which the liver does not properly process a substance called bilirubin. Bilirubin is made by the break down of red blood cells.

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HCV/HIV Coinfection

HCV/HIV coinfection means that a person has both viruses at the same time. For every 100 people with HIV, approximately 21 of them also have HCV.

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Hemochromatosis

Hemochromatosis is an inherited condition in which the body absorbs and stores too much iron that builds up in several organs, especially the liver, and can cause serious damage.

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Hepatic Encephalopathy

Hepatic Encephalopathy (HE), sometimes referred to as portosystemic encephalopathy or PSE, is a condition that causes temporary worsening of brain function in people with advanced liver disease.

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Hepatitis A

Hepatitis A virus (HAV) usually goes away on its own in almost all cases with no serious complications. However, HAV may cause some patients to suffer liver failure.

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Hepatitis B

About 95% of adults who are exposed to Hepatitis B virus (HBV) fully recover within 6 months (acute) without medication. About 5% have it all their lives (chronic) unless they are successfully treated.

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Hepatitis C Information Center

Hepatitis C is a virus that affects the liver. It is the leading cause of liver failure and end stage liver disease and is a major cause of liver transplants in the United States.

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Hepatitis D

Hepatitis Delta (HDV) is one of several infections that can cause damage to the liver. (Others include hepatitis A, B, C). HDV harms liver cells causing inflammation (swelling).

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Hepatocellular Carcinoma

Hepatocellular carcinoma is the most common type of cancer among adults in the USA. Most people with hepatocellular carcinoma have many small clusters of cancer cells called nodules.

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Hepatorenal Syndrome

Hepatorenal Syndrome (HRS) is a life-threatening condition that affects kidney function in people with advanced liver disease.

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Intrahepatic Cholestasis of Pregnancy (ICP)

Although it has been reported as early as 5 weeks pregnant, it is more common for it to begin in the third trimester, when hormone concentrations are at their highest levels.

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Jaundice in Newborns

Jaundice is the yellowing of the skin and eyes. It results from having too much bilirubin in the blood. Bilirubin is a yellow substance made from the breakdown of red blood cells.

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Liver Cysts

Liver cysts are abnormal sacs filled with fluid in the liver.

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Lysosomal Acid Lipase Deficiency (LALD)

Lysosomal acid lipase deficiency affects the body’s ability to produce this enzyme needed to breakdown fat and cholesterol. When LAL is missing, fats accumulate and lead to liver and heart disease.

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Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic fatty liver disease (NAFLD) is the build up of extra fat in liver cells that is not caused by alcohol.

Note: NAFLD is now called Metabolic Dysfunction Associated Steatotic Liver Disease, (MASLD).

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Nonalcoholic Steatohepatitis (NASH)

NASH tends to develop in people who are overweight or obese, or have diabetes, high cholesterol or high triglycerides. However, some people have NASH even if they do not have any risk factors.

Note: NASH is now called metabolic dysfunction associated steatohepatitis (MASH).

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Pediatric Liver Information Center

Find disease specific information, patient stories, videos, activities, educational resources and more! Access the online site as a parent, teen or child to view age-appropriate information.

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Rare Disease

Some diseases of the liver are much more uncommon and rare to occur, but when they do it takes a skilled team to diagnose and treat it.

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Treatment

There exists a variety of different treatment options based upon the type of liver disease.

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Viral Hepatitis

Viral hepatitis is liver inflammation due to a viral infection. It may present in acute form as a recent infection with relatively rapid onset, or in chronic form.

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Wilson Disease

Wilson Disease causes the body to retain excess copper. The liver of a person who has Wilson Disease does not release copper into bile as it should.

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